Publications

Selected Publications

Liao, P., Yang, E.J., and Pon, L.A. (2020). Live-cell imaging of mitochondrial redox state in yeast cells. STAR Protoc. 1(3):100160. {Pubmed Link}

Garcia, E.J., Liao, P., Tan, G., Vevea, J.D., Sing, C.N., Tsang, C.A., McCaffery, J.M., Boldogh, I.R., and Pon, L.A. (2020). Membrane dynamics and protein targets of lipid droplet microautophagy during ER stress-induced proteostasis in budding yeast, Saccharomyces cerevisiae. Autophagy. Oct 6:1-21. {Pubmed Link}

Liao, P., Wolken, D.M.A, Serrano, E., Srivastava, P., and Pon, L.A. (2020). Mitochondria-associated degradation pathway (MAD) function beyond the outer membrane. Cell Rep. 32(2):107902. {Pubmed Link}

Liao, P., Higuchi-Sanabria, R., Swayne, T.C., Sing, C.N., and Pon, L.A. (2020). Live-cell imaging of mitochondrial motility and interactions in Drosophila neurons and yeast. Methods Cell Biol. 155:519-544. {Pubmed Link}

Garcia, E.J., de Jonge, J.J., Liao, P., Stivison, E., Sing, C.N., Higuchi-Sanabria, R., Boldogh, I.R., and Pon, L.A. (2019) Reciprocal interactions between mtDNA and lifespan control in budding yeast. Mol Biol Cell. 30(24):2943-2952.  {Pubmed Link}

Liao, P., Boldogh, I.R., Siegmund, S.E., Freyberg, Z., and Pon, L.A. (2018) Isolation of mitochondria from Saccharomyces cerevisiae using magnetic bead affinity purification. PLoS One. 13(4): e0196632. {Pubmed Link}

Garcia, E.J., Vevea, J.D., and Pon, L.A. (2018) Lipid droplet autophagy during energy mobilization, lipid homeostasis and protein quality control. Front Biosci. 23:1552-1563. {Pubmed Link}

Hirabayashi, Y., Kwon, S.K., Paek, H., Pernice, W.M., Paul, M.A., Lee, J., Erfani, P., Raczkowski, A., Petry, D.S., Pon, L.A, and Polleux, F. (2017) ER-mitochondria tethering by PDZ8 regulates Ca2+ dynamics in mammalian neurons. Science. 358(6363):623-630 {Pubmed Link}

Pernice, W.M., Vevea, J.D., and Pon, L.A. (2016) A role for Mfb1p in region-specific anchorage of high-functioning mitochondria and lifespan in Saccharomyces cerevisiae. Nature Commun. 7:10595 {Pubmed Link}

Higuchi-Sanabria, R., Vevea, J.D., Charalel J.K., Sapar M.L., Pon L.A. (2016) The transcriptional repressor Sum1p counteracts Sir2p in regulation of the actin cytoskeleton, mitochondrial quality control and replicative lifespan in Saccharomyces cerevisiae. Microb Cell. 3(2):79-88 {PubMed Link}

Higuchi-Sanabria R, Charalel JK, Viana MP, Garcia EJ, Sing CN, Koenigsberg A, Swayne TC, Vevea JD, Boldogh IR, Rafelski SM, Pon LA. (2016) Mitochondrial anchorage and fusion contribute to mitochondrial inheritance and quality control in the budding yeast Saccharomyces cerevisiae. Mol Biol Cell. 27(5):776-87 {PubMed Link}

Higuchi-Sanabria R, Garcia EJ, Tomoiaga D, Munteanu EL, Feinstein P, Pon LA. (2016) Characterization of Fluorescent Proteins for Three- and Four-Color Live-Cell Imaging in S. cerevisiae. PLoS One. 11(1):e0146120 {PubMed Link}

Vevea JD, Garcia EJ, Chan RB, Zhou B, Schultz M, Di Paolo G, McCaffery JM, Pon LA. (2015) Role for Lipid Droplet Biogenesis and Microlipophagy in Adaptation to Lipid Imbalance in Yeast. Dev Cell. 35(5):584-99 {PubMed Link}

Wolken DM, McInnes J, Pon LA. (2014) Aim44p regulates phosphorylation of Hof1p to promote contractile ring closure during cytokinesis in budding yeast. Mol Biol Cell. 25(6):753-62 {PubMed Link}

Higuchi, R., Vevea, J.D., Swayne, T.C., Chojnowski, R., Hill, V., Boldogh, I.R., and Pon, L.A. (2013) Actin dynamics affect mitochondrial quality control and aging in budding yeast. Curr Biol. 23:2417-22 {PubMed Link}

Vevea JD, Swayne TC, Boldogh IR, Pon LA (2014) Inheritance of the fittest mitochondria in yeast. Trend Cell Biol. 24(1):53-60 {PubMed Link}

Vevea JD, Alessi Wolken DM, Swayne TC, White AB, Pon LA (2013) Ratiometric biosensors that measure mitochondrial redox state and ATP in living yeast cells. J Vis Exp. (77):50633 {PubMed Link}

Pon, LA (2013) Mitochondrial fission: rings around the organelle. Curr Biol. 23(7):R279-81 {PubMed Link}

Crider, D.G., *Garcia-Rodriguez, L.J., Peraza Reyes, C.L., Srivastrava, P., Upadhyaya, K., Boldogh, I.R., and Pon, L.A. (2012) Rad53 is essential for a mitochondrial DNA inheritance checkpoint regulating G1 to S progression, J. Cell Biol. 198:793-798. {PubMed Link}

Swayne, T.C., Zhou, C., Boldogh, I.R., Charalel, J.R., McFaline-Figueroa, J.R., Thoms, S., Yang, C., Leung, G. McInnes, J., Erdmann, R. and Pon, L.A. (2011) Role for cER and Mmr1p in anchorage of mitochondria at sites of polarized surface growth in budding yeast, Curr Biol. 21:1994-1999 {PubMed Link}

Pon LA (2011) Organelle transport: mitochondria hitch a ride on dynamic microtubules. Curr Biol. 21(17):R654-6 {PubMed Link}

McFaline-Figueroa JR, Vevea J, Swayne TC, Zhou C, Liu C, Leung G, Boldogh IR, Pon LA. (2011) Mitochondrial quality control during inheritance is associated with lifespan and mother-daughter age asymmetry in budding yeast. Aging Cell. 10(5):885-95 {PubMed Link}

Peraza-Reyes L, Crider DG, Pon LA. (2011) Mitochondrial manoeuvres: latest insights and hypotheses on mitochondrial partitioning during mitosis in Saccharomyces cerevisiae. Bioessays. 32(12):1040-9 {PubMed Link}

Area-Gomez E, de Groof AJ, Boldogh I, Bird TD, Gibson GE, Koehler CM, Yu WH, Duff KE, Yaffe MP, Pon, L.A., Schon EA. (2009) Presenilins are enriched in endoplasmic reticulum membranes associated with mitochondria. Am J Pathol. Epub 2009 Oct 15. {PubMed Link}

Garcia-Rodriguez LJ, Crider DG, Gay AC, Salanueva IJ, Boldogh IR, Pon, L.A. (2009) Mitochondrial inheritance is required for MEN-regulated cytokinesis in budding yeast. Curr Biol. 19:1730-5. {PubMed Link}

Pon LA (2008) Golgi inheritance: rab rides the coat-tails. Curr Biol. 18(17):R743-R745 {PubMed Link}

Boldogh IR, Pon LA (2007) Mitochondria on the Move. Trends Cell Biol. 17(10):502-10 {PubMed Link}

Garcia-Rodriguez, L.J., Gay, A.C., and Pon, L.A. (2007) Puf3p is a mitochondrial protein that regulates mitochondrial biogenesis and motility in budding yeast, J. Cell Biol., 176:197-207. {PubMed Link} 

Mitochondria, 2nd Edition. Methods in Cell Biology. (2007) Pon, L.A. and E.A Schon, editors. Elsevier Press.

Huckaba, T.M., Lipton, T., and Pon, L.A. (2006) Roles of type II myosin and a tropomyosin isoform in retrograde actin flow in budding yeast, J. Cell Biol.,175:957-69. {PubMed Link}

Fehrenbacher, K., Boldogh, I.R., and Pon, L.A. (2005) A role for Jsn1p in recruiting Arp2/3 complex to mitochondria in budding yeast Mol. Biol. Cell 16:5094-5102. {PubMed Link}

Boldogh IR, Fehrenbacher KL, Yang HC, Pon LA (2005) Mitochondrial movement and inheritance in budding yeast. Gene. 354:28-36 {PubMed Link}

Fehrenbacher, K.L., Yang, H-C., Gay, A.C., Huckaba, T.M., andPon, L.A. (2004) Live cell imaging of mitochondrial movement along actin cables in budding yeast. Curr Biol. 14:1996-2004. {PubMed Link}

Huckaba, T.M., Gay, A.C., Pantalena, L.F., Yang, H-C., and Pon, L.A. (2004) Live cell imaging of the assembly, disassembly, and actin cable-dependent movement of endosomes and actin patches in the budding yeast, Saccharomyces cerevisiae. J. Cell Biol. 167:519-30. {PubMed Link}

Boldogh, I.R., Ramcharan, S., and Pon, L.A. (2004) A type V myosin (Myo2p) and a Rab-like G-protein (Ypt11p) are required for retention of newly inherited mitochondria in yeast cells during cell division. Mol. Biol. Cell. 15:3994-4002. {PubMed Link}

Boldogh, I.R., Nowakowski, D., Yang, H-C., Chung, H., Karmon, S., Royes, P., and Pon, L.A. (2003) A protein complex containing Mdm10p, Mdm12p and Mmm1p links mitochondrial membranes and DNA to the cytoskeleton-based segregation machinery. Mol Biol Cell. 14:4618-4627. {PubMed Link}

Fehrenbacher, K., Boldogh, I.R. and Pon, L.A. (2003). Taking the A-train: actin-based force generators and their organelle targeting. Trends Cell Biol. 13:472-477. {PubMed Link}

Huckaba, T. and Pon, L.A. (2003). Rho and Formins: cytokinetic ringleaders. Curr Biol. 12:R813-4. {PubMed Link}

Fehrenbacher, K.L., Davis, D., Wu, M., Boldogh I. and Pon, L.A. (2002). ER dynamics, inheritance and cytoskeletal interactions in budding yeast. Mol Biol Cell. 13:854-65. {PubMed Link}

Yang, H-C., and Pon, L.A. (2002) Actin cable dynamics in budding yeast. Proc Natl Acad Sci, USA. 99:751-756.{PubMed Link}

Boldogh, I., Nowakowski, W.D., Yang, H-C., Karmon, S.L., Hayes, L., Yates, J., andPon, L.A. (2001) The Arp2/3 complex is required for actin-based mitochondrial motility in yeast. Proc Natl Acad Sci, USA. 98:3162-3167.  {PubMed Link}

Yang, H-C., Palazzo, A., Swayne, T.C. and Pon, L.A. (1999). A retention mechanism for distribution of mitochondria during cell division in budding yeast. Curr Biol. 9:1111-1114.  {PubMed Link}

Boldogh, I., Vojtov, N., Karmon, S.L. and Pon, L.A. (1998). Interaction between Mitochondria and the Actin Cytoskeleton in Budding Yeast Requires Two Integral Mitochondrial Outer Membrane Proteins, Mmm1p and Mdm10p. J Cell Biol. 141:1371-1382. {PubMed Link}

Anderson, B.L., Boldogh, I., Evangelista, M., Boone C., Greene, L.A. and Pon, L.A. (1998). The Src Homology Domain 3 (SH3) of a Yeast Type I Myosin, Myo5p, Binds to Verprolin and Is Required for Targeting to Sites of Actin Polarization. J Cell Biol. 141:1357-1370. {PubMed Link}

Goodson, H.V., Anderson, B.L., Warrick, H.M., Pon, L.A. and Spudich, J.A. (1996). Synthetic lethality screen identifies a novel myosin I gene, MYO5: myosin I proteins are required for organization of the Actin cytoskeleton. J Cell Biol. 133:1277-1291. {PubMed Link}

Full List of PubMed Publications